How is Depo-Provera given?
150 mg of Depo-Provera is given intramuscularly every 13 weeks. The contents should be shaken well and administered intramuscularly into the deltoid or gluteus maximus with a needle 2.5-4.0 cm in length and 21-23 gauge. Depo-Provera is provided in both a 50mg/ml solution and a 150mg/ml solution. The advantage of the 150mg/ml dose is that it is dispensed in a smaller volume than 3 vials of the 50 mg dose making it the better and less painful choice for deltoid injection.