How is collagen hydrolysate absorbed and how does it reach the cartilage?
Oesser et al. (Journal of Nutrition 129: 1891-95; 1999) conducted experiments with isolated segments of the intestine which have shown that collagen fragments can pass through the intestinal wall (10-15% of these proteins; in a high molecular form of up to 50kD) and reach the blood stream. Accumulation of radio-labelled collagen hydrolysate can subsequently be seen in cartilage.