How is Canine Lymphoma Treated?
Multi-agent chemotherapy is the current standard option for treatment of lymphoma. Canine lymphoma is one of the most responsive cancers to chemotherapy. Other treatment options include single-agent chemotherapy or treatment with prednisone alone. Although multi-agent chemotherapy has been shown to significantly prolong the survival time of many animals with lymphoma, there is a need for treatment options that will result in long-term control, and possibly a chance for cure. Investigational Opportunity for Dogs with Lymphoma We are currently enrolling dogs in a clinical study using a novel drug called a PAR protein (PARP) inhibitor in combination with conventional chemotherapy agents. This treatment option is being tested to determine if it increases the effectiveness of standard chemotherapy improving long-term survival without adding significant toxicity. PARP is an enzyme that is used by cells to repair DNA damage. This enzyme may be upregulated in cancer cells, allowing the cancer
