How is autosomal recessive inheritance different?
Both parents must pass on the same or similar gene defects for children to inherit a recessive disease. If one gene in a pair is normal and the other defective, the person is a carrier. Carriers of genetic defects have minimal, if any, disease symptoms.Children of parents who each carry a gene for the same recessive disease have a 25 percent chance of inheriting two flawed genes and therefore developing the disease. These diseases are unlikely to be due to spontaneous mutations, since two mutations have to occur to produce the disease. How does inheritance work in X-linked recessive diseases? X-linked diseases are those that come from gene defects on the X chromosome. These disorders affect males almost exclusively, because males have only one X chromosome. This means they have no “backup” copy of a normal gene on a second X chromosome. Females have two X chromosomes, so a gene defect on one of them usually doesn’t pose much of a problem. A normal gene on the female’s other X chromosom
