How is Alfaxan® metabolised in the body?
Alfaxan® is metabolised rapidly in the liver. Alfaxalone has a very short plasma elimination half-life in dogs and cats4,5 Alfaxalone is completely cleared from the body within a few hours after single administration 4,5 When Alfaxan® is administered as a repeated bolus or as total intravenous anaesthesia (TIVA) as a continuous rate infusion, alfaxalone levels do not accumulate and recovery periods do not appear to be prolonged6. This supports the claim that the repeated use of the product over a short period of time (for procedures lasting for up to one hour7) does not present a risk of accumulation.
