How important is it to have a muscle biopsy if someone has MH in the family?
The muscle biopsy is the only reliable diagnostic test for MH at the present time. If it is not possible to perform this test, members of the family should be considered MH susceptible and managed accordingly. The muscle biopsy is important for ruling out MH susceptibility in various family members and their offspring because if a patient is MH negative, their offspring will also be MH negative. However, if they are MH positive, their offspring will have a 50% likelihood of being MH susceptible.
