How has the epidemiology of Clostridium difficile (C. difficile) infections (CDI) changed?
Over the past several years nationwide, states have reported increased rates of C. difficile infection, noting more severe disease and an associated increase in mortality. CDI remains a disease mostly associated with healthcare (at least 80%) Patients most at risk remain the elderly, especially those using antibiotics. Although the elderly are still most affected, more disease has been reported in traditionally ‘low risk’ persons such as healthy person in the community and peripartum women.
