How, exactly, might taking SAM-e improve a persons mood?
Researchers have identified several possibilities. Normal brain function involves the passage of chemical messengers between cells. SAM-e may enhance the impact of mood-boosting messengers such as serotonin, norepinephrine, and dopamine – either by regulating their breakdown or by speeding up production of the receptor molecules they latch on to (Serotonin is the neurotransmitter the drugs like Prozac elevate). SAM-e may also make existing receptors more responsive. These molecules float in the outer membranes of brain cells like swimmers treading water in a pool. If the membranes get thick and glutinous, due to age or other assaults, the receptors lose their ability to move and change in response to chemical signals. By methylating fats called phospholipids, SAM-e keeps the membranes fluid and the receptors mobile. Recent Research and Updates on SAM-e In a recent study of the effects of SAM-e on depression, arthritis, and liver disease conducted by Health and Human Services’ Agency fo
