HOW DOES VIOXX WORK?
In the body, 2 enzymes are called COX-1 and COX-2. COX-1 helps regulate normal cell function in the stomach and blood. COX-2 plays a role in causing arthritis pain and inflammation by causing the release of specific compounds into the blood called cytokines. Cytokines are compounds that lead to pain and inflammation of joint tissue. VIOXX is a scientific breakthrough; the first product to target only the COX-2 enzyme. By inhibiting COX-2 those compounds that lead to inflammation and pain are inhibited from being released into the blood. Top HOW EFFECTIVE IS VIOXX? OSTEOARTHRITIS: VIOXX was evaluated for the treatment of the signs and symptoms of Osteoarthritis of the knee and hip. The effectiveness of placebo (sugar pill) was compared with VIOXX treated patients in controlled clinical trials of 6 to 86 weeks duration that enrolled approximately 3900 patients. In patients with Osteoarthritis, treatment with VIOXX 12.5 mg and 25 mg once daily resulted in an improvement in patient and phy
