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Tri-Luma® Cream (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) has three active ingredients that work together and may help lighten the dark spots associated with moderate to severe melasma. In clinical studies, 38% and 13% of subjects who had moderate to severe melasma and were treated with Tri-Luma® Cream had clear skin in 8 weeks.
