How does touch DNA processing differ from low copy number (LCN)?
LCN is used on items where only minimal contact has occurred or there are only small quantities of cells/DNA present. Differently from touch DNA processing these samples go through a higher number of PCR cycles which can obtain a DNA profile where conventional PCR would not. LCN work has to be done in special hoods and there is a higher chance of getting mixed profiles. LCN is usually only used on a sample that has already been processed, has an indication of DNA present, but cannot be re-worked any further using standard DNA methods.
