How does the structure of a protein affect regulation of enzyme activity?
Structure of a protein has everything to do with regulation of enzyme activity! You can think of protein (and therefore enzymes) working by fitting in with different proteins and biological molecules. They can have “pockets” where biochemical agents fit together and mediate/speed up the reaction. So, essentially, the structure of a protein is what gives its enzymatic activity! If you are thinking of a protein’s regulation on a separate enzyme, proteins often bind enzymes to control their activity. This can increase or decrease enzymatic activity depending on how the protein is affecting the enzyme’s active site, binding site, and a slew of other factors. But again, the interaction depends heavily on the structure (think shape) of the protein and enzyme and whether they fit in a certain conformation. Additionally, this structure can be lower order (amino acid sequence, beta sheet or helix) or higher order (the general globular shape) and is also strongly affected by the chemical make up
