How does the SPM2/SPM5/SPM8 design matrix affect ICA?
Solution: SPM design matrix doesn’t effect ICA process or run analysis step in GIFT (unless you are using the semi-blind ICA method). The SPM design matrix is used to sort components temporally. A detailed explanation of how SPM design matrix is used is given in appendix section of the Walk-through or in the HTML help manual (When you click Help button in the toolbox, the HTML help manual will open).