How does the NextBio rank results for my tissue, disease or compound of interest?
NextBio uses a combination of its proprietary rank-based statistics and various meta-analysis techniques to compute the most significant genes and biogroups associated with a tissue, disease, or a compound under investigation. To perform this calculation, NextBio combines all studies related to a given topic to identify the most significant genes and functional trends. This enables you to glean information from the standpoint of “collective experimental intelligence”. On the top of the Data Correlations results page, you can see a list of the best-correlated genes and biogroups for your search term, and a list of all the relevant studies below. When you select a ranked gene or a biogroup of interest, you can then access a subset of studies related to your original term but limited to those matching the selected gene or biogroup.
