How does the Family Finder program account for the centromere?
The Bioinformatics team treats the centromeres as SNP Poor regions. We use a hard stop for matching across each centromere. This assures that DNA segments (blocks) are truly Identical by Descent (IBD) and not Identical by State (IBS). If you seem to have an IBD segment that crosses the centromere, we evaluate it as two segments, one on each side of the centromere.
Related Questions
- If I open an Arizona Family College Savings Program account, will the beneficiary still be eligible for financial aid?
- Does the Population Finder program use DNA segments the way Family Finder does? Does it use individual SNPs?
- How many SNPs does the Family Finder program use to determine an Identical By Descent (IBD) segment?
