How Does Tenofovir React With Other Drugs?
Tenofovir can interact with other drugs or supplements you are taking. These interactions can change the amount of each drug in your bloodstream and cause an under- or overdose. New interactions are constantly being identified. Make sure that your health care provider knows about ALL drugs and supplements you are taking. Tenofovir results in higher blood levels of didanosine (Videx). ddI and tenofovir should not be used together, especially in patients with a high viral load and a low CD4 count. Serious ddI side effects may result. Tenofovir blood levels increase if it is taken with the protease inhibitors atazanavir (Reyataz) and lopinavir/ritonavir (Kaletra). This can increase the risk of tenofovir side effects. Tenofovir decreases blood levels of atazanavir. Ritonavir should be taken when atazanavir is taken with tenofovir. Tenofovir does not affect blood levels of methadone, ribavirin or adefovir. There is no known interaction between tenofovir and buprenorphine. Three regimens con
