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How does Staphylococcus aureus become resistant to methicillin?

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How does Staphylococcus aureus become resistant to methicillin?

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MRSA strains carry an extra gene (mecA) that encodes a penicillin binding protein (called PBP2a) that replaces the wildtype penicillin binding proteins when any drug related to penicillin is present.

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