How does SPMD size affect the sampling rate of a chemical?
SPMD sampling rates are directly proportional to SPMD membrane surface area. For example, a standard 1-g triolein SPMD (surface area 450 cm2) may extract 5 L of water per day for a PCB congener, whereas a standard triolein SPMD with half the surface area 225 cm2 (0.5-g of lipid) can be expected to extract 2.5 L of water per day of the same congener, assuming similar conditions for the exposures.
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