How does Rituxan Work?
RA occurs when the body’s immune system attacks the body’s joints. B-cells—a type of white blood cell found in the immune system—are thought to play an important role in this attack. Unlike other RA treatments, Rituxan works by targeting specific B-cells and reducing their count in the blood. This limits the immune system’s attack, which limits the pain, symptoms, and joint damage of RA. Because B-cells usually help the body fight infection, treating with Rituxan may increase your risk of infection.