How Does Rimantadine Work?
It is thought that rimantadine works by inhibiting the uncoating of the flu virus, an important step in the replication (the “reproduction”) of the virus. Specifically, rimantadine inhibits the activity of the influenza virus M2 protein, which forms a channel in the virus membrane. As a result, the virus cannot replicate (make copies of itself) after it enters a human cell.