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How does Retention Time Locking (RTL) screening software work?

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How does Retention Time Locking (RTL) screening software work?

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When used with the G1049A RTL Pesticide library, the GC/MS data is acquired using a method provided with the library (RTLPEST.M). The software then uses a narrow RT window to compare ions near the expected elution times in the library to those in the acquired data file. Retention times and ion abundance are used to determine possible hits. The result review functionality is based on the “Enhanced” mode Qedit feature and simplifies the interactive review/ confirmation process.

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