How does replacement gene therapy work?
Replacement gene therapy displaces a mutated gene, most often a tumor suppressor gene, and replaces it with a normal copy of that gene which function to control cell growth and division. The p53 gene, the most known and common gene altered in cancer has turned out to be a prime target for replacement of gene, and has been successful in preventing cell growth, preventing angiogenesis that is the development of a tumor’s blood supply, and to induce apoptosis.
Replacement gene therapy displaces a mutated gene, most often a tumor suppressor gene, and replaces it with a normal copy of that gene which function to control cell growth and division. The p53 gene, the most known and common gene altered in cancer has turned out to be a prime target for replacement of gene, and has been successful in preventing cell growth, preventing angiogenesis that is the development of a tumor s blood supply, and to induce apoptosis.
Replacement gene therapy helps to eradicate, or displace mutated genes – those which are often responsible for cancerous tumor growth – and replaces them with normal copies of those genes. These healthy gene “copies” potentially help to control cell growth and division. The most known and common gene altered in cancer is the “p53 gene.
