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How does policosanol help maintain normal cholesterol?

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How does policosanol help maintain normal cholesterol?

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A number of controlled clinical studies performed on animals and human volunteers has shown that policosanol, a mixture of fatty alcohols derived from sugar cane wax (Saccharum officinarium), helps maintain normal cholesterol and lipoprotein levels. Favorable actions on maintaining healthy levels of both “bad” LDL and “good” HDL cholesterol are seen. Some studies report benefits on maintaining normal serum triglycerides although others report no effect. Although the exact mechanism of action is unknown, policosanol appears to affect enzymes that regulate cholesterol synthesis. It also inhibits the oxidation of LDL cholesterol that is part of the process contributing to inflammation and hardening of the arteries. Increased exercise tolerance and favorable actions on platelet function are also seen following policosanol administration.

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