How does Periostat® work to treat periodontitis?
Periostat® is an entirely unique approach to the treatment of periodontitis. It fights the deterioration of support tissue around the tooth. When Periostat® is prescribed in combination with deep cleaning therapies (scaling and root planing), clinical trials have shown significant reduction in tooth pocket depth and improved tooth attachment. In untreated periodontitis, bacteria-containing plaque and calculus accumulate. This bacterial invasion triggers collagenase production to fight the bacteria; collagenase is an enzyme directly responsible for tissue destruction. Periostat® suppresses the enzymes that cause periodontal breakdown and prevents the enzymes from further breaking down the gum and bone tissue around the teeth. With Periostat® + SRP, the activity of the destructive enzymes is reduced and the body works to restore the damaged tissue.
