How does Pain Ease work? What is the mechanism of action?
Pain Ease is a topical aerosol anesthetic skin refrigerant. When topically applied to the skin or intact mucous membranes, Pain Ease creates an instantaneous cooling effect on the surface of the site by immediate evaporation of the product. The coldness decreases the nerve conduction velocity of the C fibers and A-delta fibers that make up the peripheral nervous system. This interrupts the nociceptive (stimuli to the brain giving rise to sensations of pain) inputs to the spinal cord. This process temporarily numbs that area. The fast evaporation rate is created by Pain Eases chemical blend and its unique delivery system*. 3.) How long do I need to spray Pain Ease on the procedure site? Spray Pain Ease to the site for 4 to 10 seconds from a distance of 3 to 7 inches until the skin begins to blanch. The length of time will depend on the skins sensitivity to cold plus a number of variables such as differences in blood flow, sensory perception, weight, fat content, metabolism etc. The prac
