How does osmolarity correlate to Dry Eye Disease?
Normal osmolarities are typically found at a mean value of 302 mOsms/L, mild/moderate osmolarity (Dry Eye) at a mean of 315 mOsms/L and severe osmolarity (Dry Eye) at a mean of 336 mOsms/L. Osmolarity values in the low end of the abnormal range should be considered together with symptoms for a definitive dry eye diagnosis. Values in the upper range of normal (for the general population) e.g. 308-315, in the presence of symptoms should suggest early/mild DED.
