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How does mustard gas remove guanine from DNA?

April 26, 2017dna Gas guanine mustard remove

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How does mustard gas remove guanine from DNA?

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Belen Hurle, Ph.D.: Mustard gas is a very reactive intermediate and is particularly negative to cellular health as it has a strong tendency to bond to the guanine nitrogen in DNA strands. This leads to either immediate cellular death or, as recent research has found, cancer. Mustard gas is not very soluble in water but is very soluble in fat, contributing to its rapid absorption into the skin.