How does mosaic Down syndrome happen?
Ordinarily, when an egg and a sperm are joined at conception, a single cell is created with a total of 46 chromosomes. These chromosomes are copied, the copies are separated, and the cell then divides to create two identical daughter cells. The chromosomes in these two cells are copied, the copies divide and four cells are created. These four cells become eight cells. Eight cells become 16 cells, and so on.