How does metoclopramide work?
Metoclopramide lowers the effect of dopamine in the chemo-emetic trigger zone, thereby preventing messages from being sent to the vomiting centre of the brain. The result is a reduction in nausea and vomiting. It furthermore speeds the passage of food through the stomach into the intestine, which physically helps to prevent vomiting. Fast facts Drug schedule: schedule 4 Available as: metoclopramide is available as tablets, syrup and as an injection What does it do? metoclopramide relieves nausea and vomiting Overdose risk: medium Dependence risk: low Is metoclopramide available as a generic? yes Is metoclopramide available on prescription only? yes User information Onset of effect: within 60 minutes Duration of action: up to 6 hours Stopping this medicine: this medication can be safely stopped when no longer needed Prolonged use: metoclopramide is generally not used for prolonged periods of time; tardive dyskinesia may be observed with prolonged use Special precautions Consult your doc
