How does methadone work for phantom pain?
methadone doesn’t really “block” the sensation of being “high”. Methadone is a narcotic, like opiates and at the levels used for chronic pain opiates will not make a patient feel “high” generally after a few doses, as you build a tolerance (your body gets used to the meds). All opiates, including methadone, work in your nervous system to effect the neurochemical signals so that the dopamine and other chemicals opiates cause to be released disrupt or overpower the transmission of pain signals to the brain. Methadone does not work for everyone, for some people it will have little to no effect, either in reducing their pain or giving them a “high” sensation. speaking from personal experience, I never felt better or even a difference on much higher doses than you are taking. you may either need a higher dose to reach a threshold of active medication in your system to begin feeling relief. There are many other long-acting pain medications to try with your doctors guidance which may work for