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How does Ketoconazole / generic Nizoral work?

April 26, 2017generic ketoconazole Nizoral

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How does Ketoconazole / generic Nizoral work?

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Nizoral is an imidazole antifungal agent used to treat fungal infections. Ketoconazole inhibits the fungal cytochrome P450 enzyme lanosterol 14-demethylase and thus impairs ergosterol synthesis leading to a cascade of membrane abnormalities in the fungus. This mechanism of action makes Nizoral an effective agent in the treatment of fungal infections.