How does histoplasma cause ocular histoplasmosis syndrome?
Histoplasma capsulatum (histo) spores spread from the lungs to the eye, lodging in the choroid, a layer of blood vessels beneath the retina. There, the organism predisposes your eye to develop fragile, abnormal blood vessels that can leak, bleed, and cause scaring. If the lesion is close to the center of the retina (the macula), then vision loss ensues.
