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How does grapefruit juice interact with certain medications?

April 26, 2017certain Grapefruit interact juice medications

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How does grapefruit juice interact with certain medications?

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Grapefruit juice and fresh grapefruit contain a natural substance that suppresses an intestinal enzyme known as CYP3A. The enzyme is responsible for metabolizing certain medications. When CYP3A interacts with the natural substance in grapefruit juice, the process increases the absorption of some orally administered medications into the bloodstream. This process may increase the risk of potential side effects.