How does fluoroquinolone resistance affect management of this epidemic strain?
Increased fluoroquinolone resistance does not affect the management of infections caused by this strain. Fluoroquinolones have never been recommended for treatment of C. difficile infection and susceptibility testing is performed only as a part of an epidemiological investigation. However, resistance to fluoroquinolones may provide the epidemic strain with an advantage over susceptible strains to spread within healthcare facilities where these antibiotics are commonly used.