How does EBI contribute to the development of statistical and analytical methods of microarray results?
The main resource that directly addresses statistical and analytical methods of microarray results is Expression Profiler. Expression Profiler allows the user to perform data pre-processing (e.g. normalization, transformation) and data analysis such as clustering, pattern discovery, statistics (thru R), machine-learning algorithms and visualization. In your opinion, how far are we towards optimizing and standardizing microarray procedures so that biologic interpretation and decision-making are not based on unreliable data? This has been addressed early on and has become one of the major investments in order to increase data quality. Several people working at the EBI on expression data have also being deeply involved in such efforts. The ultimate goal of data quality assessment is to optimize microarray procedures so that significant results in biologically meaningful context can be extracted. Dr.
