How Does DXM Cause its Psychoactive Effects?
DXM binds to at least four sites in the brain (58), which can be arbitrarily labelled DM1, DM2, DM3, and DM4. There may be a fifth binding site (DM5). The following table lists the binding affinity of DXM, DTG, and 3-PPP (58), (+)-pentazocine sensitivity (60), and haloperidol displacement ability (58) (binding values in nM unless otherwise specified). “Low” means micromolar binding affinity.
