How does curcumin work against cancer?
Numerous mechanisms have been described for the anticancer activity of Curcumin. Inhibition of proliferation of tumor cells, induction of apoptosis (a mode of cell death), inhibition of transformation of cells from normal to tumor, invasion of invasion and metastasis and suppression of inflammation, have been linked with the anticancer activity of Curcumin. Downregulation of COX2, 5-LOX, adhesion molecules, inflammatory cytokines, chemokines, growth factor receptors, VEGF and transcription factors by Curcumin have been linked to its anti-tumor activity.