How does Crinone 8% work?
Crinone 8% comes in the form of a bioadhesive gel. This gel is squeezed from an applicator into the vagina. Once in the vagina, the gel attaches to the vaginal wall, enabling patients to stand and go about their normal routine immediately after application, where progesterone is absorbed and transported to the uterus. Even if the applicator is not inserted all the way to the cervix, gently squeezing the bulb will direct the gel towards the cervix. The applicator is designed to deliver the correct amount of gel with a gentle squeeze. A small amount of gel will be left in the applicator after administration. This is normal. In addition, normal movement between the vaginal walls will spread the gel. Crinone 8% should not be applied at the same time as other local vaginal treatments. If other local intravaginal therapy is to be used, it should be administered at least 6 hours before or after Crinone 8% administration. Regular sexual activity has not been found to lessen the effectiveness o
