How does cPPT aid in transduction into non-dividing cells?
The mechanism by which the Central Polypurine tract helps translocation into the nucleus of nondividing cells is not well understood, but it is known that the central polypropylene tract allows the virus to penetrate the nuclear membrane. Some useful links to literature: bloodjournal.org , liebertonline.com Return to top. Return to pGIPZ faq.