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How does Clostridium perfringens type A toxoid work?

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How does Clostridium perfringens type A toxoid work?

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Clostridium perfringens type A toxoid is administered to hens at 10 to 15 weeks of age, followed by revaccination at 17 to 20 weeks of age. The toxoid initiates high antibody titers against the alpha toxin of C. perfringens, which is the cause of NE. The antibodies are transferred to progeny chicks via the egg yolk. Antibody titers in hens are maintained throughout the laying period of 65 weeks.

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