How does carnosine prolong life span?
Similar anti-senescence effects have now been demonstrated in mice. A Russian study tested the effect of carnosine on life span and indicators of senescence in senescence-accelerated mice. Half the mice were given carnosine in their drinking water starting at two months of age. Carnosine extended the life span of the treated mice by 20% on average, compared to the mice not fed carnosine. Carnosine did not alter the 15 month maximum life span of the senescence-accelerated mice strain, but it did significantly raise the number of mice surviving to old age. The mice given carnosine were about twice as likely to reach the ripe old age of 12 months as untreated mice. It also improved indicators of senescence measured at the old age of ten months.