How does CAPE work in blocking the formation of tumours?
A. The major anti-cancer compound is called CAPE, a caffeic acid derivative. The CAPE content of Bio 30 Propolis is the highest among the propolis samples around the world that we tested. CAPE blocks an enzyme (actually a kinase) called PAK1 which activates this type of cancer. There is a huge family of PAK types. We refer to it just as PAK. Around 30% of cancers are known to be resistant to anti-PAK drugs, because those types of cancer depend on another enzymes. So there are some cancers which are resistant to Bio 30 — most of the leukaemias, lung cancer, also colon cancer. PAK is responsible for about 70% of cancers, including major cancers like breast cancer and prostrate cancer. Also several formidable cancers like pancreatic cancer and melanoma, for which there is no effective therapeutic available on the market. So we are targeting those tumours.
