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How does anti-D immunoglobulin work to treat ITP?

April 26, 2017anti-d immunoglobulin ITP treat

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How does anti-D immunoglobulin work to treat ITP?

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A. Anti-D immunoglobulin (or anti-D) is used in patients who cannot tolerate or do not respond to initial treatment with corticosteroids or IVIG. Patients receiving anti-D must have Rh-positive blood and must not have had a splenectomy. It is believed that anti-D forms red blood cell (RBC) complexes that block the destruction of the targeted platelets.