How does angioedema of the skin manifest itself?
Areas most commonly affected by swellings include the face, hands, feet, arms, legs and genital organs. In persons with bradykinin-mediated angioedema, swellings develop gradually over the course of several hours. In addition, pruritus (itching) is usually absent, although these kinds of angioedema are often associated with a feeling of tightness and sometimes also with pain.