How do you know if vaccine virus that must be frozen won’t die when you add diluent that has been stored in the refrigerator or in a cabinet?
The vaccine can be used as long as you follow the manufacturer’s guidelines for reconstitution and use. For example, MMR vaccine must be used within 8 hours of reconstitution and varicella vaccine must be used within 30 minutes of reconstitution. The manufacturer’s package insert provides very specific information regarding reconstitution, storage and handling.