How do we use beta-blocker in treatment of heart failure even though it causes inhibition of heart properties? What are the cases in which we use it?
Beta blockers have both beneficial and deleterious effects in heart failure: The deleterious effects: they deprive the heart from the sympathetic drive and thus they can induce heart failure, The beneficial effects: they inhibit the renin secretion (which elevates the ABP); decrease myocardial O2 needs and improves diastolic perfusion of the heart (prolongs diastole); up regulate the beta-1 receptors in the heart (which is needed for the sympathetic system to stimulate the heart), suppress the arrhythmic events which are major cause of mortality in heart failure …etc Accordingly we use them cautiously: the patient should be asymptomatic & if symptomatic he should have no or minimal evidence of fluid retention, should be supported with an ACE inhibitor, & should not have required recent intravenous inotropic therapy. They also should not be initiated until at least 2 weeks after hospital discharge for the patient conditions to be stable. Although they are expected to increase the hear
Related Questions
- How do we use beta-blocker in treatment of heart failure even though it causes inhibition of heart properties? What are the cases in which we use it?
- Why are condition-specific discharge instructions important following treatment for heart failure?
- What heart failure treatment options are on the horizon?
