How do we know that glucosamine and chondroitin are effective used topically?
A. Published studies on topical glucosamine have demonstrated outcomes of reduced joint pain, less stiffness and increased function of the affected joints. J Rheumatol. 2003 Nov;30(11)2512. A radonmized, double blind, placebo controlled trial of a topical cream containing glucosamine sulfate, chondroitin sulfate, and camphor for ostearthritis of the knee. CONCLUSION: Topical applicatiion of glucosamine and chondroitin sulfate is effective in relieving the pain from OA of the knee and improvement within 4 weeks.