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How do we know that glucosamine and chondroitin are effective used topically?

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How do we know that glucosamine and chondroitin are effective used topically?

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A. Published studies on topical glucosamine have demonstrated outcomes of reduced joint pain, less stiffness and increased function of the affected joints. J Rheumatol. 2003 Nov;30(11)2512. A radonmized, double blind, placebo controlled trial of a topical cream containing glucosamine sulfate, chondroitin sulfate, and camphor for ostearthritis of the knee. CONCLUSION: Topical applicatiion of glucosamine and chondroitin sulfate is effective in relieving the pain from OA of the knee and improvement within 4 weeks.

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