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How do we interpret the presence of 6-Acetylmorphine (6-AM) in oral fluid or urine?

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How do we interpret the presence of 6-Acetylmorphine (6-AM) in oral fluid or urine?

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Generally this is interpreted as administration of heroin, especially if the concentrations are large. It has been reported however that very small amounts of 6-AM can be present with very high concentrations of morphine in urine. As a contaminant, 6-AM is present much in less than 1 percent of the morphine concentration, so this possibility must be examined before concluding heroin use.

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