How do Ultrasonic Health & Beauty Devices work in conjunction with topical compounds?
-Transdermal delivery of topical compounds using Ultrasound has the potential to be an extremely efficient delivery mechanism. Topical application avoids the effects of both gastric degradation and hepatic first-pass metabolism. The epidermis represents a large surface area for absorption, has relatively low proteolytic activity and is undoubtedly one of the most easily accessible organs of the body [Ref. 2]. -Ultrasound energy produces a mechanical pressure wave through soft tissue. This pressure wave may cause microscopic bubbles in living tissues, and distortion of the cell membrane, influencing ion fluxes and intracellular activity. When ultrasound enters the body, it causes molecular friction and heats the tissues slightly. This effect is very minor as normal tissue perfusion dissipates heat. With high intensity, it can also cause small pockets of gas in body fluids or tissues to expand and contract/collapse in a phenomena called microcavitation [Ref. 3]. Ultrasonic cavitation alt