How do the retinoids rank in efficacy?
Dr. Tanghetti: Of the retinoids that are available, Avage® seems to be the strongest and most effective. A recent trial compared Renova® with Avage® in 186 patients with photodamaged skin.1 The study evaluated 50% or greater improvement, and Avage® came out on top, producing a quicker, more complete response. There was a suggestion that the response was better in all areas, but the trial was designed to answer only 1 question: “Does Avage® work quicker and more completely at 50% or greater improvement?” The answer is yes. Dr. Lupo: In our practice, we’ve found that compared with Retin-A Micro® and Renova®, Avage® produces the best results. It improves photoaging and minimizes the appearance of the pores. Moreover, it softens overall skin texture and diminishes the cobblestoned appearance, or elastosis, of sun-damaged skin. Moderator: Retinoids in general can cause irritation. How do you manage this irritation to get the best results? Dr. Tanghetti: Retinoids do cause irritation. This i
